p16INK4A as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrepTM smears

p16 as a marker for cervical dyskaryosis: CIN and cGIN in cervical biopsies and ThinPrepTM smears

Aim: To examine the potential of p16 as a biomarker for dysplastic squamous and glandular cells of the cervix in tissue sections and ThinPrepTM smears. Methods: Immunocytochemical analysis of p16 expression was performed on 22 normal cervical tissue samples, five cervical glandular intraepithelial neoplasia (cGIN), 38 cervical intraepithelial neoplasia 1 (CIN1), 33 CIN2, 46 CIN3, and 10 invasiv...

Cervical Glandular Intraepithelial Neoplasia (CGIN)

passivity in waiting for godot and endgame: a psychoanalytic reading

this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...

p16INK4A expression in cervical intraepithelial neoplasia and cervical cancer

Introduction: Cervical cancer is the third most common cancer among women and is more common in developing countries such as India, due to lack of good screening tests. The efficacy of the Pap smear is hampered by high inter-observer variability and high false positive and false negative rates. Liquid based cytology has not been shown to improve sensitivity or specificity when compared to Pap s...

Cervical neoplasia in pap smears: risk of cervical intra-epithelial neoplasia (CIN) after negative or no prior smears in a population without a mass screening programme.

BACKGROUND The aim of this study was to examine, in a population not submitted to mass screening, the risk of cancer and cervical intra-epithelial neoplasia (CIN) in Pap smears from women without previously reported positive smears. METHODS In a logistic regression model consisting of 58,271 smears from 40,536 Norwegian women the risk of cytologically indicated CIN was studied according to ag...